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Image of the Month (2010-6)

Granulomatous Lobular Mastopathy - evolution of the lesion



Clinically suspicious breast lump in a 40 year old female

Low and medium power views showing intense lobulocentric chronic inflammation - 'Mouse over' - green arrow points at epithelium of TDLU, blue arrow to cluster of giant cells within lumen - probably an early phase of the lesion

Granulomatous Lobular Mastopathy
Detail of lobulocentric inflammatory focus above with luminal giant cells

adenosis tumour - low power


Further evolution of the process with loss of lobular units, chronic inflammation and giant cells (arrows)
Granulomatous Lobular Mastopathy - medium power

End stage focus with complete loss of lobular eoithelium, fibrosis and scattered giant cells (mouse over)
Granulomatous Lobular Mastopathy - detail


See also Inflammatory lesions of the breast.

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