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Image of the Quarter (2013-1)



High grade DCIS arising in an area of columnar cell change



50 year old woman - screen-detected microcalcs - excision biopsy. 'Mouse-over' for closer view.
The duct(s) show an early micropapillary architecture and columnar cell cyto-morphology.



High grade DCIS in arising in an area of columnar cell hyperplasia



These closer views show high grade malignant nuclear features: pleomorphism, chromatin clumping and prominent nucleoli. 'Mouse-over' for closer view.


High grade DCIS in arising in an area of columnar cell hyperplasia

This adjacent duct also shows features of high grade DCIS but with apocrine features.

High grade DCIS with apocrine features



See also another case of Carcinoma in situ on this site.




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