HOME PAGE PRACTICE & PROTOCOLS INVESTIGATIONS BENIGN / BORDERLINE MALIGNANT CASE MATERIAL

Image of the Quarter (2014-3)



Flat epithelial atypia



50 year old woman - small screen-detected calcs - core biopsy.




This (top) image shows columnar cell change with mild /minimal cytological atypia. The 'Mouse-over' image shows some hyperplasia (lower left with architectural complexity). The upper right hand duct has a flat proliferation of columnar cells. The majority of cells in this image show more rounded, enlarged nuclei with some variation of nuclear size (pleomorphism) and prominence of nucleoli. Note the luninal calcs.

Flat epithelial atypia



These closer views further illustrate the changes described above. 'Mouse-over' for closer view. All the cells retain their basic columnar cell phenotype and when seen in the context of a flat lesion it is designated flat epithelial atypia. Necrotic debris is present in the two lower ducts in the top image - a feature which should give rise to concern in itself.

Flat epithelial atypia



Note:





See also... Columnar Cell Change on this site.


See also... Columnar cell hyperplasia and atypia (1) & Columnar cell hyperplasia and atypia (2) on this site.
Return to top of this page

Image of the week index

Return to Home Page