Image of the Quarter (2016-2)
60 year old screener - 5mm mammographic opacity - core biopsy.
This low power view shows a well demarcated small lesion comprising a network of channels containing red blood cells.
'Mouse-over' for a closer view.
These views show the cytologically bland nature of the endothelial linikng cells.The 'Mouse-over' shows weak birefringence with polarised light.
Smooth muscle actin immunostaining shows an intact pericyte layer around endothelial channels. This is a useful and readily available stain for the evaluation of vascular lesions. The'Mouse-over'shows further detail.
Haemangiomas of the breast are normally small and circumscribed and may be recognised as such mammographically. They are uncommon. They are distinguished from atypical vascular lesions (AVL) by being larger and better
circumscribed and from both AVL and angiosarcoma by being circumscribed, showing a lack of cytological atypia and maintaining an intact well formed pericytic layer throughout.